Etanidazole
Tīmeklisetanidazole. ChEBI ID. CHEBI:75473. Definition. A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1 H -imidazol-1-yl)acetic acid … TīmeklisEtanidazole is a 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of …
Etanidazole
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Tīmeklis1991. gada 1. febr. · Abstract. Tumor cell survival assay in the FSaIIC murine fibrosarcoma demonstrated that when the modulator Fluosol-DA (0.3 ml; 12 ml/kg i.v.) was administered just prior to an alkylating agent plus carbogen breathing for 6 h or the modulator etanidazole (1 g/kg i.p.) was administered just prior to an alkylating agent, … TīmeklisThe two radiosensitizers etanidazole and pimonidazole, currently in clinical phase 3 trials, have different toxicities. The former produces a peripheral neuropathy after …
Tīmeklis1998. gada 1. jūn. · Four dose levels of etanidazole between 3 and 5.5 g/m2/day (12, 16, 20, and 22 g/m2 total doses) and two doses of carboplatin (1600 and 1800 mg/m2 total doses) were evaluated. Seven patients died of organ toxicity (13%); two each from veno-occlusive disease of liver and sepsis; and one each from sudden death, renal … TīmeklisA nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.
Tīmeklis1989. gada 21. jūn. · The antitumor efficacy of adding the nitroimidazole radiosensitizing drugs misonidazole and etanidazole or hyperthermia (43 degrees C for 30 min) to … TīmeklisClayden, Jonathan; Greeves, Nick; Warren, Stuart; Wothers, Peter (2001). Organic Chemistry (I изд.). Oxford University Press. ISBN 978-0-19-850346-0.; Smith ...
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Tīmeklis2024. gada 11. janv. · 依他硝唑用途. Etanidazole (SR-2508) is a 2-nitroimidazole drug with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant … flights from new york to varadero cubaTīmeklis2024. gada 19. jūl. · POSTED ON JULY 19. The US Food and Drug Administration (FDA) has approved fexinidazole as the first all-oral treatment for both stages of the … flights from new york to vermontTīmeklis1996. gada 15. janv. · Hypoxia can be monitored by measuring the binding of 2-nitroimidazoles. We have tested the hypothesis that binding of EF5, a fluorinated derivative of the 2-nitroimidazole, Etanidazole, can predict radioresistance in individual tumors. Fischer rats bearing 9L s.c. tumors were given injections i.v. with EF5 3 h … flights from new york to utahTīmeklis2024. gada 21. dec. · Etanidazole is a kind of hypoxic radiosensitizer (a drug that sensitizes tumour cells to radiation therapy). Etanidazole is used in conjunction with Paclitaxel (P132500) to treat glioma, and is also used with Carboplatin (C177500) to treat advanced ovarian cancer. Definition flights from new york to williamsportTīmeklis化学物質「エタニダゾール」の詳細情報です。j-global 科学技術総合リンクセンターは研究者、文献、特許などの情報をつなぐことで、異分野の知や意外な発見などを支援する新しいサービスです。またjst内外の良質なコンテンツへ案内いたします。 cherokee nation name searchTīmeklis治疗性纳米缀合物及其用途专利检索,治疗性纳米缀合物及其用途属于··以特殊物理形式为特征的例如乳液微囊脂质体专利检索,找专利汇即可免费查询专利,··以特殊物理形式为特征的例如乳液微囊脂质体专利汇是一家知识产权数据服务商,提供专利分析,专利查询,专利检索等数据服务功能。 cherokee nation museum tahlequahTīmeklis1991. gada 1. maijs · Etanidazole, however, gave a DMF of 1.92 (1.59-2.32) with a tumor concentration of approximately 0.32 mumoles/g and 1.69 (1.46-1.96) with a … flights from new york to wv