2024 Fetal resorption in mice

Fetal resorption in mice

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WebSep 18, 2024 · Key cell types necessary for early pregnancy, as demonstrated by mouse models, include dendritic cells, which are essential for decidualization, and macrophages, which are essential for maintenance of the corpus luteum in the ovary. NK cells directly surround the trophoblasts after implantation. WebIn mice, daily treatment with pregabalin 500, 1250, or 2500 mg/kg did not induce maternal or developmental toxicity at the highest dose evaluated of 2500 mg/kg with a maternal C …

Anticardiolipin in Porphyromonas gingivalis Antisera Causes Fetal …

WebPROBLEM: This study was designed to examine the influence of age, environment, and lymphocyte immunotherapy on fetal resorption rates in the CBA/J × DJA/2J mouse model. METHODS: After weaning, CBA/J female mice were randomly allocated to two different environments: room A was a conventional housing facility, and room B was a specific … WebIntrauterine growth restriction (IUGR) is another pregnancy complication that occurs in up to 10% of infants, making fetal growth restriction the second leading cause of perinatal … structural change order somerset

Bilateral uterine vessel ligation as a model of intrauterine growth ...

WebCompared to the control, the Pgf knockout pregnant mice showed a prominently higher embryo resorption rate at embryonic day 13.5 (Figure 5A), as well as a lower IL-10 production (Figure 5B), a lower STAT3 phosphorylation at Tyr 705 (Figure 5C), and a lower C/EBPβ expression (Figure 5D) in uterine macrophages at embryonic day 8.5. These … WebFetal resorption (also known as fetus resorption) is the disintegration and assimilation of one or more fetuses in the uterus at any stage after the completion of … WebNotably, injection of mouse bone marrow-derived DCs (BM-DCs) rescued the cytochrome c-evoked embryo resorption. The present study suggests cytochrome cinjection causes embryo resorption in mice, hinting caution regarding the use of cytochrome c … structural change and aggregate growth

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Maternal Exposure to Polystyrene Micro- and Nanoplastics Causes …

WebBacteria were washed in PBS, re-suspended in PBS containing alum at approximately 2 × 10 8 /mL, and heated to 80 o C for 10 min. A 50-μg quantity of bacterial suspension was … WebApr 23, 2009 · To assess the importance of TF in fetal death and growth restriction in CBA/J × DBA/2 mice, we inhibited TF with a rat monoclonal anti-mTF antibody 1H1. 16 Administration of 1H1 was associated with a significant decrease in fetal resorption frequency (Figure 2A) and prevention of IUGR at day 15 of pregnancy (Figure 2B). structural cells functionWebMouse; View all Topics. Add to Mendeley. Set alert. About this page. Pregnancy. ... Abortion or fetal resorption occurred within 2 to 6 days after operations in all 14 mares ovariectomized between Days 25 and 45 and after an interval of 10 to 15 days in 9 of 20 other ovariectomized between 50 and 70 days. All 12 mares ovariectomized on either ... structural ceiling beams

"WebJan 9, 2024 · Study outline. In the current study, we describe the histology and immunohistochemistry of spontaneous resorptions, which were identified by reduced growth rate and reduced heart rate in daily scans of pregnant mice with high-resolution ultrasound in a previous study [].The pathological details of the implantation sites under resorption … " - Fetal resorption in mice

Fetal resorption in mice

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WebJul 8, 2014 · Thus, litter size was reduced in test mice. Fetal resorption was also precisely analyzed by comparing the number of fetuses found at the day of surgery and the number of fetus alive at E18.5. P3 presented the highest rate of fetal resorption with 37%, while P2 resorption rate was 0% (Table 1). P1 revealed an intermediate situation with 25% of ... WebRecent studies demonstrated that the vaccination of mice with cDNA encoding the capsid proteins of TMEV could alter the course of TMEV-induced demyelinating disease. A …

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WebConversely, decidual accumulation of maternal T cells with fetal specificity and fetal wastage were extinguished by CXCR3 blockade or in CXCR3-deficient mice. Remarkably, protection against fetal ... WebEnter the email address you signed up with and we'll email you a reset link.

WebIn mouse models of Listeria monocytogenes, infection is sufficient to recruit fetal-specific CD8 + T cells to the placenta and cause fetal demise (Chaturvedi et al., 2015). Thus, … WebApr 4, 2016 · All surviving females were euthanized on GD 18 or GD 30 for mice and rabbits, respectively, and examined grossly: the number of corpora lutea, location and status of the implant site (live or dead fetus, early or late resorption), and sex and individual weight of each live fetus was recorded.

WebAssessment of Fetal Resorption. To determine the effects of antibody preparations on fetal loss, we intravenously infused purified IgG preparations (40 μg) into the tail veins of naïve mated BALB/c females at day 0 of pregnancy, and determined the percentage of fetal resorptions in the mouse groups as described previously (Blank et al., 2002 ... WebInbred strains of mice are powerful models for understanding human pregnancy complications. For example, the exclusive mating of CBA/J females to DBA/2J males …

WebStudies in mice have shown that either immunization with β 2-GPI or the passive transfer of aPL promotes fetal resorption, fetal death, reduced litter sizes, and …

WebIn the uterus from mice treated with LPS and progesterone we observed embryos in various stages of resorption. Some of them were healthy, other underdeveloped and with a … structural cells of the nervous systemWebAug 18, 2024 · Tight transcriptional regulation of HLA-C expression allows balancing between the induction of tolerance and alloimmunity at the maternal-fetal junction (23). In mice, alloimmune recognition of maternal T cells was exclusively through maternal antigen-presenting cells (APCs), which uptake and process the fetal antigens. structural change in organizationWebThe objective of this study was to test the hypothesis that both in vitro and in vivo, preimplantation embryonic development and postimplantation fetal development are impaired in superovulated female mice when compared with naturally cycling controls. structural change and economic dynamics期刊WebApr 29, 2013 · The extensive application of nanomaterials in industry, medicine and consumer products has raised concerns about their potential toxicity. The female population is particularly vulnerable and deserves special attention because toxicity in this group may impact both female reproductivity and fetal development. Mouse and zebrafish models … structural channel dimensions astm a36WebJun 1, 2001 · Since embryonic and fetal growth retardation have been described after superovulation in mice, the aim of this study was to determine whether this negative effect is induced by impaired oocyte and/or embryo quality, or by abnormal blastocyst formation in the stimulated oviductal and/or uterine environment. structural changes during pregnancyWebJun 1, 2012 · Fetal DNA is sensed by TLR9 to induce fetal resorption. (A) TLR9-deficient mice are resistant to fetal DNA as shown by measurement of fetal resorption in pregnant C57bl/6 wild-type and C57bl/6 TLR9-deficient mice administered i.p. fetal DNA on gestation day 10–14 and sacrificed 48 h later. structural change growth and volatilityWebIn this study, we investigated the effect of maternal exposure to plastics on fetal and placental growth using experimental mice. The dams exposed to plastics received either … structural changes in organization