WebPhD thesis: "The role of dopamin in the pathogenesis of HIV-associated dementia", Publications: "Memantine upregulates BDNF and prevents dopamine deficits in SIV … WebThe pharmacological effect of memantine likely occurs via the drug's behavior as an uncompetitive (open-channel) NMDA receptor antagonist, preventing glutamate action on this receptor. Memantine has a preference for the NMDA receptor-operated …
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WebChen HS, Pellegrini JW, Aggarwal SK et al (1992) Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. J Neurosci 12:4427–4436 WebACTION AND CLINICAL PHARMACOLOGY Persistent activation of the central nervous system N-methyl-D-aspartate (NMDA) receptors by the excitatory amino acid glutamate … find my cellular provider
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