Pdz domain-containing protein gipc1
Splet21. mar. 2024 · GIPC1 (GIPC PDZ Domain Containing Family Member 1) is a Protein Coding gene. Diseases associated with GIPC1 include Oculopharyngodistal Myopathy 2 and … CDH1 (Cadherin 1) is a Protein Coding gene. Diseases associated with CDH1 … DDIT3 (DNA Damage Inducible Transcript 3) is a Protein Coding gene. Diseases … SDC4 (Syndecan 4) is a Protein Coding gene. Diseases associated with SDC4 … DRD2 (Dopamine Receptor D2) is a Protein Coding gene. Diseases associated with … Although the BCR-ABL fusion protein has been extensively studied, the function of … PRKCA (Protein Kinase C Alpha) is a Protein Coding gene. Diseases associated with … NPLOC4 (NPL4 Homolog, Ubiquitin Recognition Factor) is a Protein Coding … Splet(Click on the icon in the table below to see search hit context)
Pdz domain-containing protein gipc1
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Splet24. avg. 2008 · A human monoclonal autoantibody to breast cancer identifies the PDZ domain containing protein GIPC1 as a novel breast cancer-associated antigen We have determined that GIPC1 is a novel breast cancer-associated immunogenic antigen that is overexpressed in breast cancer. SpletThe hedgehog (Hh) pathway is essential for animal development, but aberrant activation promotes cancer growth. In this study, we show that GIPC3, a PDZ domain-containing protein with putative adaptor protein function, positively modulates Hh target gene expression in normal fibroblasts and melanoma cells and supports melanoma tumor …
Splet04. mar. 2024 · NMR structure of GIPC1-GH2 domain PDB DOI: 10.2210/pdb7NRN/pdb BMRB: 34609 Classification: ENDOCYTOSIS Organism (s): Mus musculus Expression System: Escherichia coli Mutation (s): No Deposited: 2024-03-04 Released: 2024-04-14 Deposition Author (s): Barthe, P., Roumestand, C. Experimental Data Snapshot Method: … Splet07. jun. 2013 · The PDZ domain of GIPC1 is involved in direct interactions with a variety of proteins, including adrenergic receptor β1 (ADRB1), 35 APPL1, 36, 37, 38 CD93 (C1QR1), …
SpletPDZ domain-containing protein GIPC2 Alternative names SemaF cytoplasmic domain-associated protein 2 ( SEMCAP-2) Gene names Name Gipc2 Synonyms Semcap2 Organism names Organism Mus musculus (Mouse) Taxonomic … Splet22. jun. 2005 · The data presented support our earlier proposed adapter function for GLUT1CBP(GIPC1) (Bunn et al., 1999) and provide a basis for a refined model wherein movement of a cargo protein bound to the PDZ domain of GLUT1CBP(GIPC1) is mediated through interactions of its C-terminal domain with the tail of the myosin VI motor protein. …
SpletHearing relies on the transduction of sound-evoked vibrations into electrical signals, occurring in the stereocilia bundle of inner ear hair cells. The G protein-coupled receptor (GPCR) ADGRV1 and the multi-PDZ protein PDZD7 play a critical role in the formation and function of stereocilia through their scaffolding and signaling properties. During hair cell …
Splet29. mar. 2024 · GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]). [supplied by OMIM, Apr … download all latest punjabi songs 2019SpletSPA-1, a PDZ domain-containing protein, was demonstrated to have GTPase-activating protein activity for AQP2 trafficking . Thus, for the understanding of the function of the … clarins.atSpletPurpose: Various studies have shown the importance of the GAIP interacting protein, COOH-terminus (GIPC, also known as Synectin) as a central adaptor molecule in different signaling pathways and as an important mediator of receptor stability. download all latest movies freeSpletGIPC is a PDZ domain–containing protein. The the apoptotic effects of p53 activity and subsequently protein–protein interactions mediated by PDZ-containing increase cell survival. ... Kirikoshi H, Katoh M. Expression of human GIPC1 in normal tissues, suppresses breast cancer progression through GIPC-mediated inhi- cancer cell lines, and ... download all latest musicSpletPDZ domains are protein-interaction domains that are often found in multi-domain scaffolding proteins. PDZ-containing scaffolds assemble specific proteins into large molecular complexes at defined locations in the cell. In the postsynaptic density of neuronal excitatory synapses, PDZ proteins such a … clarins batomSplet29. mar. 2024 · GIPC1 is a novel breast cancer-associated immunogenic antigen that is overexpressed in breast cancer GIPC1 protein is overexpressed in ovarian and breast … clarins basilic patchouliSplet11. jan. 2013 · The cytoplasmic plaque of the TJs contains other PDZ domain containing proteins as well. These include AF6/afadin, MUPP1 (multi-PDZ-domain protein), MAGI (membrane associated guanylate kinase inverted) -1, -2 and -3 and PAR-3 and -6. These proteins also bind other proteins of the junctional complex, but their role in the regulation … clarins batch code checker